WebTBK1 control PROTAC ® 4 is a negative control for TBK1 PROTAC ® 3i (Cat. No. 7259). Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC … WebIndeed, the cyclic guanosine monophosphate-adenosine monophosphate synthase‒stimulator of interferon genes‒TANK-binding kinase 1 (cGAS‒STING‒TBK1) axis is now appreciated as the major signaling pathway in innate immune response across different species.
Small molecules targeting the innate immune cGAS‒STING‒TBK1 …
Web8 dic 2024 · TBK1 PROTAC 3i. Protein target name: TBK1. Mechanism of action: Degrader PROTAC. Recommended Concentration for use in cells: up to 1 uM . Reviewer suggested Concentration for use in cells: ... cpd 3i, PROTAC. PubChem CID: 124108661. ChEMBL ID: CHEMBL4227907. SMILES string: WebBiological Activity: Negative control for TBK1 PROTAC® 3i (Cat. No. 7259). Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. goodwins queensferry street
TBK1 control PROTAC® 4 Cas# 2052306-31-5 - GlpBio
WebARV-471 ER-targeting PROTAC® protein degrader ER+/HER2- Metastatic Breast Cancer Phase 1 Product Enhancement Ibrance + ARV-471 CDK 4,6 kinase inhibitor ER-targeting PROTAC® protein degrader ER+/HER2- Metastatic Breast Cancer Phase 1 … WebSTING agonist-28 (CF510) is a non-nucleotide small-molecule STING agonist. STING agonist-23 activates STING, increases phosphorylation of STING, TBK1 and IRF3. STING agonist-23 promotes the levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-5 in tumor cells. STING agonist-23 exhibits activity against SARS-CoV series strains. - Mechanism … Web6 mag 2024 · Product Name: TBK1 PROTAC® 3i Formula: C53H74BrN9O9S Molecular Weight: 1093.19 CAS Number: 2052306-13-3 4. FIRST AID MEASURES 4.1 Description of first aid measures General advice Consult a doctor and show this safety data sheet. If inhaled Remove to fresh air and monitor breathing. If breathing becomes difficult, give … goodwins princeton ky